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Molecular subtype and tumor characteristics of breast cancer metastases as assessed by gene expression significantly influence patient post-relapse survival.

Journal article
Authors N P Tobin
J C Harrell
J Lövrot
S Egyhazi Brage
M Frostvik Stolt
L Carlsson
Zakaria Einbeigi
Barbro Linderholm
N Loman
M Malmberg
T Walz
M Fernö
C M Perou
J Bergh
T Hatschek
L S Lindström
Published in Annals of oncology : official journal of the European Society for Medical Oncology / ESMO
Volume 26
Issue 1
Pages 81-8
ISSN 1569-8041
Publication year 2015
Published at
Pages 81-8
Language en
Subject categories Cancer and Oncology


We and others have recently shown that tumor characteristics are altered throughout tumor progression. These findings emphasize the need for re-examination of tumor characteristics at relapse and have led to recommendations from ESMO and the Swedish Breast Cancer group. Here, we aim to determine whether tumor characteristics and molecular subtypes in breast cancer metastases confer clinically relevant prognostic information for patients.

Page Manager: Webmaster|Last update: 9/11/2012

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