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Radiation Therapy to the Plexus Brachialis in Breast Cancer Patients: Analysis of Paresthesia in Relation to Dose and Volume.

Journal article
Authors Dan Lundstedt
Magnus Gustafsson
Gunnar Steineck
Agnetha Sundberg
Ulrica Wilderäng
Erik Holmberg
Karl-Axel Johansson
Per Karlsson
Published in International journal of radiation oncology, biology, physics
Volume 92
Issue 2
Pages 277–283
ISSN 1879-355X
Publication year 2015
Published at Institute of Clinical Sciences, Department of Radiation Physics
Institute of Clinical Sciences, Department of Oncology
Pages 277–283
Language en
Subject categories Cancer and Oncology


To investigate predictors of paresthesia after irradiation of the brachial plexus, we compared women treated for breast cancer with and women treated without irradiation of the brachial plexus. The plexus was delineated on dose-planning computerized tomography. The women answered a questionnaire 3 to 8 years after radiation therapy. Irradiated volumes and doses were related to the occurrence of paresthesia in the hand. Our results indicate a correlation between larger irradiated volumes of the brachial plexus and paresthesia.

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