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Immediately loaded non-submerged versus delayed loaded submerged dental implants: A meta-analysis.

Journal article
Authors B R Chrcanovic
Tomas Albrektsson
Ann Wennerberg
Published in International Journal of Oral & Maxillofacial Surgery
Volume 44
Issue 4
Pages 493-506
ISSN 0901-5027
Publication year 2015
Published at Institute of Clinical Sciences, Department of Biomaterials
Pages 493-506
Language en
Links dx.doi.org/10.1016/j.ijom.2014.11.0...
Keywords dental implants, submerged, non-submerged, one-stage implant, two-stage implant, implant failure rate, postoperative infection, marginal bone loss, meta-analysis
Subject categories Biomaterials

Abstract

The purpose of the present meta-analysis was to test the null hypothesis of no difference in the implant failure rate, postoperative infection, and marginal bone loss for patients being rehabilitated with immediately loaded non-submerged dental implants or delayed loaded submerged implants, against the alternative hypothesis of a difference. An electronic search without time or language restrictions was undertaken in March 2014. Eligibility criteria included clinical human studies, either randomized or not. The search strategy resulted in 28 publications. The inverse variance method was used for a random- or fixed-effects model, depending on the heterogeneity. The estimates of an intervention were expressed as the risk ratio (RR) and mean difference (MD) in millimetres. Twenty-three studies were judged to be at high risk of bias, one at moderate risk of bias, and four studies were considered at low risk of bias. The difference between procedures (submerged vs. non-submerged implants) significantly affected the implant failure rate (P=0.02), with a RR of 1.78 (95% confidence interval (CI) 1.12-2.83). There was no apparent significant effect of non-submerged dental implants on the occurrence of postoperative infection (P=0.29; RR 2.13, CI 0.52-8.65) or on marginal bone loss (P=0.77; MD -0.03, 95% CI -0.23 to 0.17).

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