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Glycolipids of rat small intestine. Characterization of a novel blood group H-active triglycosylceramide.

Journal article
Authors Michael Breimer
Gunnar C. Hansson
K A Karlsson
H Leffler
Published in Biochimica et biophysica acta
Volume 617
Issue 1
Pages 85-96
ISSN 0006-3002
Publication year 1980
Published at Department medicine
Pages 85-96
Language en
Keywords ABO Blood-Group System, immunology, Animals, Chemical Phenomena, Chemistry, Chromatography, Gas, Epithelium, analysis, Glycosphingolipids, analysis, Ileum, analysis, Jejunum, analysis, Magnetic Resonance Spectroscopy, Male, Mass Spectrometry, Rats, Trihexosylceramides, analysis, immunology, isolation & purification
Subject categories Clinical Medicine


A novel blood group H-active triglycosylceramide has been isolated from rat small intestine. It was present exclusively in the epithelial cells. The structure was established by mass spectrometry, NMR spectroscopy and degradative methods to the Fucp alpha 1 leads to 2Galp beta 1 leads to 4Glcp beta 1 leads to 1Cer. The lipophilic part was made up of mainly trihydroxy base (phytosphingosine) and 16 : 0--24 : 0 fatty acids.

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