To the top

Page Manager: Webmaster
Last update: 9/11/2012 3:13 PM

Tell a friend about this page
Print version

Insulin-Like Growth Facto… - University of Gothenburg, Sweden Till startsida
Sitemap
To content Read more about how we use cookies on gu.se

Insulin-Like Growth Factor-1 and Anti-Vascular Endothelial Growth Factor in Retinopathy of Prematurity: Has the Time Come?

Journal article
Authors A. Stahl
Ann Hellström
L. E. H. Smith
Published in Neonatology
Volume 106
Issue 3
Pages 254-260
ISSN 1661-7800
Publication year 2014
Published at Institute of Neuroscience and Physiology
Pages 254-260
Language en
Links dx.doi.org/10.1159/000365132
Keywords Insulin-like growth factor 1, Preterm birth, Retinopathy of prematurity, Vascular endothelial growth, POSTNATAL WEIGHT-GAIN, INTRAVITREAL BEVACIZUMAB, IGF-I, LASER, PHOTOCOAGULATION, MACULAR DEGENERATION, PRETERM INFANTS, PLASMA-LEVELS, INJECTION, ANGIOGENESIS, PREDICTION, Pediatrics
Subject categories Clinical Medicine

Abstract

Treatment of retinopathy of prematurity (ROP) is currently evolving. Novel therapeutic options are emerging that have the potential to complement existing therapies and improve treatment outcomes. However, any new therapeutic option must be thoroughly evaluated before existing (and successful) treatment paradigms can be amended. This is particularly so when switching from locally effective therapies like photoablative laser therapy to systemic pharmacological treatments, which may have hitherto unknown widespread side effects. This review compiles the current knowledge of where and when the two most advanced pharmacological treatment options for ROP, insulin-like growth factor-1 supplementation and anti-vascular endothelial growth factor treatment, may have their place in future therapy regimens for ROP. The requirement for clinical studies is emphasized: these are needed to address safety considerations before any of these interventions can achieve the status of standard clinical care in the very vulnerable population of ROP infants.

Page Manager: Webmaster|Last update: 9/11/2012
Share:

The University of Gothenburg uses cookies to provide you with the best possible user experience. By continuing on this website, you approve of our use of cookies.  What are cookies?