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Thromboembolic complications in 3544 patients undergoing radical prostatectomy with or without lymph node dissection.

Journal article
Authors Stavros I Tyritzis
Anna Wallerstedt
Gunnar Steineck
Tommy Nyberg
Jonas Hugosson
Anders Bjartell
Ulrica Wilderäng
Thordis Thorsteinsdottir
Stefan Carlsson
Johan Stranne
Eva Haglind
Nils Peter Wiklund
Jan-Erik Damber
Published in The Journal of urology
Volume 193
Issue 1
Pages 117-125
ISSN 1527-3792
Publication year 2015
Published at Institute of Clinical Sciences, Department of Surgery
Institute of Clinical Sciences, Department of Oncology
Institute of Clinical Sciences, Department of Urology
Pages 117-125
Language en
Keywords prostate; prostatectomy; lymph node excision; venous thrombosis; pulmonary embolism
Subject categories Cancer and Oncology, Urology and Nephrology


Lymph node dissection (LND) in prostate cancer patients may increase complications. An association of LND with thromboembolic events has been suggested. We compared the incidence and investigated predictors of deep venous thrombosis (DVT) and pulmonary embolism (PE) among other complications in patients undergoing or not undergoing LND during open (ORP) and robot-assisted laparoscopic radical prostatectomy (RARP) METHODS: 3544 patients were included between 2008-2011. The cohort derives from LAPPRO, a multi-center, prospective controlled trial. Data concerning adverse events were extracted from patient-completed questionnaires. Our primary outcome was prevalence of DVT and/or PE. Secondary outcomes were other types of 90-day adverse events and re-admission causes.

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