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Dental implants in irradiated versus non-irradiated patients: A meta-analysis.

Review article
Authors Bruno Ramos Chrcanovic
Tomas Albrektsson
Ann Wennerberg
Published in Head & neck
Volume 38
Issue 3
Pages 448-81
ISSN 1097-0347
Publication year 2016
Published at Institute of Clinical Sciences, Department of Biomaterials
Pages 448-81
Language en
Keywords dental implants;radiotherapy;infection;marginal bone loss;meta-analysis
Subject categories Biomaterials


Background/Methods. The purpose of the present meta-analysis was to test the null hypothesis of no difference in dental implant failure rates, postoperative infection, and marginal bone loss for patients being rehabilitated by dental implants and being previously irradiated in the head and neck region versus non-irradiated patients, against the alternative hypothesis of a difference. Results/Conclusion. The study suggests that irradiation negatively affects the survival of implants, as well as the difference in implant location (maxilla vs. mandible), but there is no statistically significant difference in survival when implants are inserted before or after 12 months after radiotherapy. The study failed to support the effectiveness of hyperbaric oxygen therapy in irradiated patients. It was observed a tendency to lower survival rates of implants inserted in the patients submitted to higher irradiation doses. The results should be interpreted with caution due to the presence of uncontrolled confounding factors in the included studies. Head Neck, 2014.

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