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Higher CSF interleukin-6 and CSF interleukin-8 in current depression in older women. Results from a population-based sample.

Journal article
Authors Silke Kern
Ingmar Skoog
Anne Börjesson-Hanson
Kaj Blennow
Henrik Zetterberg
Svante Östling
Jürgen Kern
Pia Gudmundsson
Lars Rosengren
Margda Waern
Published in Brain, behavior, and immunity
Volume 41
Pages 55-58
ISSN 1090-2139
Publication year 2014
Published at Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry
Centre for Ageing and Health (Agecap)
Pages 55-58
Language en
Links dx.doi.org/10.1016/j.bbi.2014.05.00...
https://gup.ub.gu.se/file/142441
Keywords Prospective; Population-based; CSF; Interleukin-6; Interleukin-8; Depression; Older women
Subject categories Neurochemistry

Abstract

The literature regarding cerebrospinal fluid (CSF) cytokines in geriatric depression is sparse. The aim of this study was to examine associations between CSF interleukin-6 (IL-6), interleukin-8 (IL-8) and depression in a population-based sample of older women who were followed for 17years.

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