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WINROP can modify ROP screening praxis: a validation of WINROP in populations in Sormland and Vastmanland

Journal article
Authors L. Eriksson
U. Liden
Chatarina Löfqvist
Ann Hellström
Published in British Journal of Ophthalmology
Volume 98
Issue 7
Pages 964-966
ISSN 0007-1161
Publication year 2014
Published at Institute of Neuroscience and Physiology
Pages 964-966
Language en
Links dx.doi.org/10.1136/bjophthalmol-201...
Subject categories Ophthalmology

Abstract

Background This study validates the newly developed WINROP algorithm aimed at detecting retinopathy of prematurity (ROP) requiring treatment at an early stage. The study was conducted at two middle-sized hospitals in Sweden, prospectively and retrospectively. Methods A total of 104 children participated in this study. Their mean gestational age at birth was 28.7 weeks (range, 23.6-32.1 weeks), and their mean birth weight was 1208 g (range, 477-2340 g). Weekly weight measurements were used in WINROP to calculate the risk of developing ROP. Results 80% of infants (83/104) had no ROP, 15% (16/104) had mild ROP (stage 1 or 2), 5% (5/104) had severe ROP, and 2% (2/104) were treated for ROP. The alarm was registered at an average of 2 weeks postnatal age (range 1-6 weeks). Conclusions WINROP identified all the infants at risk for developing stage 3 ROP (100% sensitivity) and had a 59% specificity. The alarm was registered several weeks before screening for ROP began. WINROP can be used to complement conventional ROP screening.

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