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Vitamin D in the General Population of Young Adults with Autism in the Faroe Islands.

Journal article
Authors Eva Kočovská
Guðrið Andorsdóttir
Pál Weihe
Jónrit Halling
Elisabeth Fernell
Tormóður Stóra
Rannvá Biskupstø
I Carina Gillberg
Robyn Shea
Eva Billstedt
Thomas Bourgeron
Helen Minnis
Christopher Gillberg
Published in Journal of autism and developmental disorders
Volume 44
Issue 12
Pages 2996-3005
ISSN 1573-3432
Publication year 2014
Published at Gillberg Neuropsychiatry Centre
Pages 2996-3005
Language en
Links dx.doi.org/10.1007/s10803-014-2155-...
Subject categories Child and adolescent psychiatry

Abstract

Vitamin D deficiency has been proposed as a possible risk factor for developing autism spectrum disorder (ASD). 25-Hydroxyvitamin D3 (25(OH)D3) levels were examined in a cross-sectional population-based study in the Faroe Islands. The case group consisting of a total population cohort of 40 individuals with ASD (aged 15-24 years) had significantly lower 25(OH)D3 than their 62 typically-developing siblings and their 77 parents, and also significantly lower than 40 healthy age and gender matched comparisons. There was a trend for males having lower 25(OH)D3 than females. Effects of age, month/season of birth, IQ, various subcategories of ASD and Autism Diagnostic Observation Schedule score were also investigated, however, no association was found. The very low 25(OH)D3 in the ASD group suggests some underlying pathogenic mechanism.

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