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Cytokine expression in patients with bladder pain syndrome/interstitial cystitis ESSIC Type 3C.

Journal article
Authors Yr Logadottir
Dick Delbro
Magnus Fall
Inger Gjertsson
Pernilla Jirholt
Catharina Lindholm
Ralph Peeker
Published in The Journal of urology
Volume 192
Issue 5
Pages 1564–1568
ISSN 1527-3792
Publication year 2014
Published at Institute of Medicine, Department of Rheumatology and Inflammation Research
Institute of Clinical Sciences, Department of Urology
Pages 1564–1568
Language en
Keywords urinary bladder, cystitis, interstitial, pain, interleukins, cytokines
Subject categories Urology and andrology


Nitric oxide (NO) production from the bladder wall in patients with Bladder Pain Syndrome (BPS) Type 3C is increased compared to undetectable NO levels in non-Hunner BPS patients and healthy controls. However, the underlying mechanism/s of the increased NO production is largely unknown. Our aim was to compare mRNA expression of a selected group of cytokines in BPS/IC Type 3C patients versus pain-free controls.

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