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N-terminal pro-B-type natriuretic peptide and long-term mortality in acute coronary syndromes.

Journal article
Authors Torbjørn Omland
Anita Persson
Leong Ng
Russel O'Brien
Thomas Karlsson
Johan Herlitz
Marianne Hartford
Kenneth Caidahl
Published in Circulation
Volume 106
Issue 23
Pages 2913-8
ISSN 1524-4539
Publication year 2002
Published at Cardiovascular Institute
Institute of Physiology and Pharmacology
Pages 2913-8
Language en
Keywords Acute Disease, Aged, Angina, Unstable, blood, diagnosis, mortality, Biological Markers, blood, Cohort Studies, Comorbidity, Coronary Artery Disease, blood, diagnosis, mortality, Female, Humans, Male, Middle Aged, Multivariate Analysis, Myocardial Infarction, blood, diagnosis, mortality, Natriuretic Peptide, Brain, Nerve Tissue Proteins, blood, Peptide Fragments, blood, Predictive Value of Tests, Prognosis, Regression Analysis, Risk Assessment, Risk Factors, Survival Rate, Survivors, statistics & numerical data, Sweden, epidemiology, Time
Subject categories Clinical Medicine


B-type natriuretic peptide (BNP) is a predictor of short- and medium-term prognosis across the spectrum of acute coronary syndromes (ACS). The N-terminal fragment of the BNP prohormone, N-BNP, may be an even stronger prognostic marker. We assessed the relation between subacute plasma N-BNP levels and long-term, all-cause mortality in a large, contemporary cohort of patients with ACS.

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