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Imatinib treatment and Aβ42 in humans.

Journal article
Authors Bob Olsson
Laurence Legros
François Guilhot
Kia Strömberg
James Smith
Frederick J Livesey
David H Wilson
Henrik Zetterberg
Kaj Blennow
Published in Alzheimer's & dementia : the journal of the Alzheimer's Association
Volume 10
Issue 5, supplement
Pages S374–S380
ISSN 1552-5279
Publication year 2014
Published at Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry
Pages S374–S380
Language en
Links dx.doi.org/10.1016/j.jalz.2013.08.2...
Keywords Aβ42, Imatinib, Plasma, CML, Alzheimer's disease
Subject categories Neurochemistry

Abstract

The first-line treatment in chronic myeloid leukemia (CML), imatinib, has been shown to decrease the production of amyloid-β (Aβ) in vitro and in animal studies. However, whether imatinib has this effect in humans is not known.

Page Manager: Webmaster|Last update: 9/11/2012
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