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High proportions of FOXP3(+) CD25(high) T cells in neonates are positively associated with allergic sensitization later in childhood.

Journal article
Authors Anna Strömbeck
Hardis Rabe
Anna-Carin Lundell
Kerstin Andersson
Susanne Johansen
Ingegerd Adlerberth
Agnes E Wold
Bill Hesselmar
Anna Rudin
Published in Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology
Volume 44
Issue 7
Pages 940–952
ISSN 1365-2222
Publication year 2014
Published at Institute of Medicine, Department of Rheumatology and Inflammation Research
Institute of Clinical Sciences, Department of Pediatrics
Institute of Biomedicine, Department of Infectious Medicine
Pages 940–952
Language en
Keywords allergic sensitization;children;farm;FOXP3+CD25high T cells;neonates;T cell development
Subject categories Pediatrics


The role of FOXP3(+) regulatory T cells in the prevention against sensitization and allergy development is controversial.

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