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Surgical treatment of recurring ameloblastoma, are there options?

Journal article
Authors Oscar Hammarfjord
Johan Roslund
Peter Abrahamsson
Peter Nilsson
Andreas Thor
Mikael Magnusson
Göran Kjeller
Charlotta Englesson-Sahlström
Tomas Strandkvist
Gunnar Warfvinge
Carina Krüger-Weiner
Published in The British journal of oral & maxillofacial surgery
Volume 51
Issue 8
Pages 762–766
ISSN 1532-1940
Publication year 2013
Published at Institute of Odontology
Pages 762–766
Language en
Keywords Ameloblastoma; Recurrent ameloblastoma; Odontogenic neoplasm
Subject categories Clinical Medicine, Surgical research, Oral pathology and forensic odontology


Our aim was to evaluate the treatment given to patients with intraosseus ameloblastomas with special emphasis on recurrence and the outcomes of primary and secondary resection. Forty-eight patients who were treated for intraosseous ameloblastoma at 8 centres across Sweden met the inclusion criteria. They showed typical distribution of age, sex, site of lesion, and characteristic presenting features. Eleven of the 48 were initially treated with radical resection and none recurred. Twenty-two of the remaining 37 who were initially treated by conservative resection presented with recurrences. Sixteen of the 22 then had conservative secondary resections, which resulted in further recurrence in 6 patients. Initial radical resection is therefore superior to conservative management as far as recurrences are concerned. We argue, however, that a conservative surgical approach is adequate for many intraosseous ameloblastomas with limited extension, because relapse can be followed by radical resection if clinically indicated in selected cases.

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