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TGF-β1 promotes transition of mesothelial cells into fibroblast phenotype in response to peritoneal injury in a cell culture model.

Journal article
Authors Peter Falk
Eva Angenete
Maria Bergström
Marie-Louise Ivarsson
Published in International journal of surgery (London, England)
Volume 11
Issue 9
Pages 977–982
ISSN 1743-9159
Publication year 2013
Published at Institute of Clinical Sciences, Department of Surgery
Pages 977–982
Language en
Keywords Adhesion formation, Mesothelial cells, Peritoneum, Transforming growth factor, Proliferation and experimental model
Subject categories Surgery


Peritoneal adhesions are a clinical problem. A key to the understanding of peritoneal adhesions is to study the healing of mesothelial cells within the peritoneal cavity following surgery. Transforming growth factor beta (TGF-βs) affects this healing process. The aim of this study was to investigate the effects of different concentrations of TGF-β1 on the healing rate and healing properties of mesothelial cells.

Page Manager: Webmaster|Last update: 9/11/2012

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