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Dual Conjugate Adaptive Optics Prototype for Wide Field High Resolution Retinal Imaging

Chapter in book
Authors Zoran Popovic
Jörgen Thaung
Per Knutsson
Mette Owner-Petersen
Published in Adaptive Optics Progress
Pages 3-21
ISBN 978-953-51-0894-8
Publisher Intech
Place of publication Rijeka
Publication year 2012
Published at Institute of Neuroscience and Physiology, Department of Clinical Neuroscience and Rehabilitation
Pages 3-21
Language en
Links dx.doi.org/10.5772/53640
Keywords adaptive optics, retina, cone, capillary, FAZ, cell density, cell separation
Subject categories Medical Engineering

Abstract

Retinal imaging is limited due to optical aberrations caused by imperfections in the optical media of the eye. Consequently, diffraction limited retinal imaging can be achieved if optical aberrations in the eye are measured and corrected. Information about retinal pathology and structure on a cellular level is thus not available in a clinical setting but only from histological studies of excised retinal tissue. In addition to limitations such as tissue shrinkage and distortion, the main limitation of histological preparations is that longitudinal studies of disease progression and/or results of medical treatment are not possible.

Adaptive optics (AO) is the science, technology and art of capturing diffraction-limited images in adverse circumstances that would normally lead to strongly degraded image quality and loss of resolution. In non-military applications, it was first proposed and implemented in astronomy. AO technology has since been applied in many disciplines, including vision science, where retinal features down to a few microns can be resolved by correcting the aberrations of ocular optics. As the focus of this chapter is on AO retinal imaging, we will focus our description to this particular field.

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