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Ciprofloxacin for 7 days versus 14 days in women with acute pyelonephritis: a randomised, open-label and double-blind, placebo-controlled, non-inferiority trial.

Journal article
Authors Torsten Sandberg
Gunilla Skoog
Anna Bornefalk Hermansson
Gunnar Kahlmeter
Nils Kuylenstierna
Anders Lannergård
Gisela Otto
Bo Settergren
Gunilla Stridh Ekman
Published in Lancet
Volume 380
Issue 9840
Pages 484-90
ISSN 1474-547X
Publication year 2012
Published at Institute of Biomedicine, Department of Infectious Medicine
Pages 484-90
Language en
Links dx.doi.org/10.1016/S0140-6736(12)60...
Keywords Acute Disease, Adult, Aged, Anti-Infective Agents, administration & dosage, Bacteriuria, etiology, microbiology, Ciprofloxacin, administration & dosage, Community-Acquired Infections, drug therapy, Double-Blind Method, Drug Administration Schedule, Drug Resistance, Microbial, Female, Follow-Up Studies, Humans, Middle Aged, Prospective Studies, Pyelonephritis, complications, drug therapy, Treatment Outcome, Withholding Treatment
Subject categories Infectious Medicine

Abstract

Acute pyelonephritis is a common infection in adult women, but there is a paucity of controlled trials of its treatment and the optimum duration of antibiotic treatment has not been properly defined. We compared the efficacy of ciprofloxacin for 7 days and 14 days in women with community-acquired acute pyelonephritis.

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