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Ex vivo measurements of mucus secretion by colon explants.

Journal article
Authors Jenny K Gustafsson
Henrik Sjövall
Gunnar C. Hansson
Published in Methods in Molecular Biology
Volume 842
Pages 237-43
ISSN 1064-3745
Publication year 2012
Published at Institute of Biomedicine
Institute of Medicine, Department of Internal Medicine and Clinical Nutrition
Institute of Biomedicine, Department of Medical Biochemistry and Cell Biology
Pages 237-43
Language en
Keywords Animals, Biopsy, Colon, secretion, Colonoscopy, Humans, Mice, Mucus, secretion, Rats
Subject categories Cell and Molecular Biology


An explant tissue system for the study and recording of mucus secretion has been developed. Human colon biopsies or tissue from experimental animals are mounted in a horizontal perfusion chamber and the mucus accumulated on the apical side is observed and measured.

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