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Efficacy of a low-cost, inactivated whole-cell oral cholera vaccine: results from 3 years of follow-up of a randomized, controlled trial.

Journal article
Authors Jan Holmgren
Published in PLoS neglected tropical diseases
Volume 5
Issue 10
Pages e1289
ISSN 1935-2735
Publication year 2011
Published at Institute of Biomedicine, Department of Microbiology and Immunology
Pages e1289
Language en
Keywords Administration, Oral, Adolescent, Child, Child, Preschool, Cholera, microbiology, prevention & control, Cholera Vaccines, administration & dosage, economics, immunology, Diarrhea, microbiology, prevention & control, Follow-Up Studies, Humans, Immunization, Secondary, methods, India, Infant, Placebos, administration & dosage, Time Factors, Vaccination, methods, Vaccines, Inactivated, administration & dosage, economics, immunology, Vibrio cholerae O1, isolation & purification
Subject categories Basic Medicine, Immunology in the medical area


Killed oral cholera vaccines (OCVs) have been licensed for use in developing countries, but protection conferred by licensed OCVs beyond two years of follow-up has not been demonstrated in randomized, clinical trials.

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