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Type-dependent E6/E7 mRNA expression of single and multiple high-risk human papillomavirus infections in cervical neoplasia.

Journal article
Authors Elin Andersson
Cecilia Kärrberg
Thomas Rådberg
Lennart Blomqvist
Britt-Marie Zetterqvist
Walter Ryd
Magnus Lindh
Peter Horal
Published in Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology
Volume 54
Issue 1
Pages 61-5
ISSN 1873-5967
Publication year 2012
Published at Institute of Biomedicine, Department of Infectious Medicine
Institute of Clinical Sciences, Department of Obstetrics and Gynecology
Pages 61-5
Language en
Links dx.doi.org/10.1016/j.jcv.2012.01.01...
Subject categories Obstetrics and women's diseases, Medical Genetics

Abstract

Coinfection with multiple HPV types is common in cervical lesions, but the biological significance of the individual infections is difficult to establish. Expression of oncogenic E6/E7 HPV mRNA is correlated to risk of malignant progression, commercial assays for genotyping E6/E7 mRNA of all HR-HPV are lacking.

Page Manager: Webmaster|Last update: 9/11/2012
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