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Childhood attention-deficit hyperactivity disorder as an extreme of a continuous trait: a quantitative genetic study of 8,500 twin pairs.

Journal article
Authors Henrik Larsson
Henrik Anckarsäter
Maria Råstam
Zheng Chang
Paul Lichtenstein
Published in Journal of child psychology and psychiatry, and allied disciplines
Volume 53
Issue 1
Pages 73-80
ISSN 1469-7610
Publication year 2012
Published at Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry
Pages 73-80
Language en
Keywords Attention Deficit Disorder with Hyperactivity, diagnosis, epidemiology, psychology, Child, Cohort Studies, Diseases in Twins, diagnosis, epidemiology, psychology, Female, Genetic Linkage, genetics, Genetic Testing, Health Surveys, methods, statistics & numerical data, Humans, Male, Prevalence, Psychiatric Status Rating Scales, statistics & numerical data, Psychometrics, Severity of Illness Index, Sweden, epidemiology, Twins, Dizygotic, genetics, psychology, statistics & numerical data, Twins, Monozygotic, genetics, psychology, statistics & numerical data
Subject categories Psychiatry


Although the clinical utility of categorically defined attention-deficit hyperactivity disorder (ADHD) is well established, there is also strong evidence supporting the notion of ADHD as an extreme of a continuous trait. Nevertheless, the question of whether the etiology is the same for different levels of DSM-IV ADHD symptoms remains to be investigated. The aim of this study was to assess genetic links between the extreme and the subthreshold range of ADHD symptoms.

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