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Impact of Obesity on the Bioavailability of Peginterferon-α2a and Ribavirin and Treatment Outcome for Chronic Hepatitis C Genotype 2 or 3.

Journal article
Authors Åsa Alsiö
Karolina Rembeck
Galia Askarieh
Peer Brehm Christensen
Martti Färkkilä
Nina Langeland
Mads Rauning Buhl
Court Pedersen
Kristine Mørch
Bart L Haagmans
Salmir Nasic
Johan Westin
Kristoffer Hellstrand
Gunnar Norkrans
Martin Lagging
Published in PloS one
Volume 7
Issue 5
Pages e37521
ISSN 1932-6203
Publication year 2012
Published at Institute of Biomedicine, Department of Infectious Medicine
Pages e37521
Language en
Links dx.doi.org/10.1371/journal.pone.003...
Subject categories Microbiology in the medical area, Clinical virology, Infectious Medicine

Abstract

Having a body mass index above or equal to 30 kg/m(2) in conjunction with chronic hepatitis C virus infection is associated with non-responsiveness to treatment with interferon and ribavirin, but details regarding the mechanisms whereby obesity reduces the efficacy of therapy remain unclear.

Page Manager: Webmaster|Last update: 9/11/2012
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