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The Child and Adolescent Twin Study in Sweden (CATSS).

Journal article
Authors Henrik Anckarsäter
Sebastian Lundström
Linnea Kollberg
Nora Kerekes
Camilla Palm
Eva Carlström
Niklas Långström
Patrik K E Magnusson
Linda Halldner
Sven Bölte
Christopher Gillberg
Clara Gumpert
Maria Råstam
Paul Lichtenstein
Published in Twin Research and Human Genetics
Volume 14
Issue 6
Pages 495-508
ISSN 1832-4274
Publication year 2011
Published at Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry
Gillberg Neuropsychiatry Centre
Pages 495-508
Language en
Links dx.doi.org/10.1375/twin.14.6.495
Keywords Adolescent, Age Factors, Attention Deficit Disorder with Hyperactivity, Diagnosis, Epidemiology, Autistic Disorder, Diagnosis, Epidemiology, Child, Diseases in Twins, Diagnosis, Epidemiology, Female, Follow-Up Studies, Humans, Interviews as Topics, Longitudinal Studies, Male, Neuropsychiatry, Obsessive-Compulsive Disorder, Diagnosis, Epidemiolgy, Parents, Prevalence, Questionnaires, Reproducibility of Results, Sex Factors, Sweden, Epidemiology, Tic Disorders, Diagnosis, Epidemiology
Subject categories Child and adolescent psychiatry

Abstract

The Child and Adolescent Twin Study in Sweden (CATSS) is an ongoing longitudinal twin study targeting all twins born in Sweden since July 1, 1992. Since 2004, parents of twins are interviewed regarding the children's somatic and mental health and social environment in connection with their 9th or 12th birthdays (CATSS-9/12). By January 2010, 8,610 parental interviews concerning 17,220 twins had been completed, with an overall response rate of 80%. At age 15 (CATSS-15) and 18 (CATSS-18), twins and parents complete questionnaires that, in addition to assessments of somatic and mental health, include measures of personality development and psychosocial adaptation. Twin pairs in CATSS-9/12 with one or both twins screening positive for autism spectrum disorders, attention deficit/hyperactivity disorder, tic disorders, developmental coordination disorder, learning disorders, oppositional defiant disorder, conduct disorder, obsessive-compulsive disorder, and/or eating problems have been followed with in-depth questionnaires on family, social environment and personality, and subsequently by clinical assessments at age 15 together with randomly selected population controls, including 195 clinically assessed twin pairs from the first 2 year cohorts (CATSS-15/DOGSS). This article describes the cohorts and study groups, data collection, and measures used. Prevalences, distributions, heritability estimates, ages at onset, and sex differences of mental health problems in the CATSS-9/12, that were analyzed and found to be overall comparable to those of other clinical and epidemiological studies. The CATSS study has the potential of answering important questions on the etiology of childhood mental health problems and their role in the development of later adjustment problems.

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