To the top

Page Manager: Webmaster
Last update: 9/11/2012 3:13 PM

Tell a friend about this page
Print version

Antiretroviral drug treat… - University of Gothenburg, Sweden Till startsida
To content Read more about how we use cookies on

Antiretroviral drug treatment of CNS HIV-1 infection.

Journal article
Authors Aylin Yilmaz
Richard W Price
Magnus Gisslén
Published in The Journal of antimicrobial chemotherapy
Volume 67
Issue 2
Pages 299-311
ISSN 1460-2091
Publication year 2012
Published at Institute of Biomedicine, Department of Infectious Medicine
Pages 299-311
Language en
Keywords cerebrospinal fluid, antiretroviral drugs, pharmacokinetics, pharmacodynamics
Subject categories Microbiology in the medical area


The advent of combination antiretroviral treatment has had a profound impact on CNS HIV infection and its clinical complications, but neurological impairment still occurs in patients on systemically effective combination therapy, and in some patients it may be important to consider antiretroviral drug entry and effects within the CNS. There are now data on the CNS exposure for most antiretroviral drugs. This review focuses on the CNS pharmacokinetics and pharmacodynamics of antiretroviral drugs in humans, and also discusses controversies in this field.

Page Manager: Webmaster|Last update: 9/11/2012

The University of Gothenburg uses cookies to provide you with the best possible user experience. By continuing on this website, you approve of our use of cookies.  What are cookies?