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Influence of five neutralizing products on intra-oral pH after rinsing with simulated gastric acid.

Journal article
Authors Birgitta Lindquist
Peter Lingström
Lars Fändriks
Dowen Birkhed
Published in European journal of oral sciences
Volume 119
Issue 4
Pages 301-4
ISSN 1600-0722
Publication year 2011
Published at Institute of Odontology
Institute of Clinical Sciences, Department of Gastrosurgical Research and Education
Institute of Odontology, Section 3
Pages 301-4
Language en
Links dx.doi.org/10.1111/j.1600-0722.2011...
Keywords Adult, Aluminum Hydroxide, pharmacology, Animals, Antacids, pharmacology, Area Under Curve, Buffers, Cariostatic Agents, pharmacology, Female, Gastric Acid, physiology, Gum Arabic, pharmacology, Humans, Hydrochloric Acid, antagonists & inhibitors, pharmacology, Hydrogen-Ion Concentration, Male, Milk, Mineral Waters, Mouth, drug effects, physiology, Mouthwashes, pharmacology, Saliva, physiology, secretion, Sodium Fluoride, pharmacology, Time Factors, Tooth Erosion, chemically induced, Water
Subject categories Cariology

Abstract

The aetiology of dental erosion may be of both extrinsic and intrinsic origin. The aim of the present study was to test the ability of various neutralizing products to raise the low intra-oral pH after an erosive exposure, in this case to gastric acid, which was simulated using hydrochloric acid (HCl). Eleven adults participated. They rinsed with 10 ml of 10 mM HCl (pH 2) or 10 ml of 100 mM HCl (pH 1) for 1 min, after which the pH was measured intra-orally for up to 30 min at four sites (two approximal, one buccal, and the dorsum of the tongue). After rinsing with the two acid solutions (pH 1 and pH 2), the following products were used: (i) antacid tablet; (ii) gum arabic lozenge; (iii) mineral water; (iv) milk; and (v) tap water (positive control). The negative control was no product use. The five test products were used for 2 min after the erosive challenge. All the products produced an initially higher pH compared with the negative control. The antacid tablet resulted in the greatest and most rapid increase in pH, followed by the lozenge. In dental practice, the use of any of the neutralizing products tested, especially the antacid tablet, could be recommended in order to increase the intra-oral pH after an erosive challenge.

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