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Severe exacerbations and decline in lung function in asthma.

Journal article
Authors Paul M O'Byrne
Søren Pedersen
Carl Johan Lamm
Wan C Tan
William W Busse
Bernt Alm
Published in American journal of respiratory and critical care medicine
Volume 179
Issue 1
Pages 19-24
ISSN 1535-4970
Publication year 2009
Published at Institute of Clinical Sciences, Department of Pediatrics
Pages 19-24
Language en
Keywords Adolescent, Adult, Aged, Asthma, drug therapy, physiopathology, Budesonide, administration & dosage, Child, Child, Preschool, Disease Progression, Double-Blind Method, Female, Forced Expiratory Volume, Glucocorticoids, administration & dosage, Humans, Male, Middle Aged, Prospective Studies, Respiratory Function Tests, Treatment Outcome, Young Adult
Subject categories Pediatrics


To evaluate the association between asthma exacerbations and the decline in lung function, as well as the potential effects of an inhaled corticosteroid, budesonide, on exacerbation-related decline in patients with asthma.

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