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Immediate occlusal loading of NanoTite PREVAIL implants: a prospective 1-year clinical and radiographic study.

Journal article
Authors Pär-Olov Östman
Ann Wennerberg
Tomas Albrektsson
Published in Clinical implant dentistry and related research
Volume 12
Issue 1
Pages 39-47
ISSN 1708-8208
Publication year 2010
Published at Institute of Clinical Sciences, Department of Biomaterials
Pages 39-47
Language en
Keywords Alveolar Bone Loss, classification, Bone Density, physiology, Calcium Phosphates, chemistry, Crowns, Dental Alloys, chemistry, Dental Implantation, Endosseous, methods, Dental Implants, Dental Implants, Single-Tooth, Dental Prosthesis Design, Dental Prosthesis Retention, Dental Prosthesis, Implant-Supported, Dental Restoration Failure, Denture Design, Denture, Complete, Immediate, Denture, Partial, Fixed, Denture, Partial, Temporary, Follow-Up Studies, Humans, Mandible, surgery, Maxilla, surgery, Nanostructures, chemistry, Osseointegration, physiology, Osteogenesis, physiology, Prospective Studies, Surface Properties, Titanium, chemistry, Torque, Treatment Outcome
Subject categories Biomaterials


BACKGROUND: Recently, a new implant surface texture, featuring application of nanometer-scale calcium phosphate has been shown to enhance early bone fixation and formation in preclinical studies and in human histomorphometric studies, which may be beneficial in immediate loading situations. AIM: The purpose of the present prospective clinical study was to, during 1 year, clinically and radiographically evaluate a nanometer scale surface modified implant placed for immediate loading of fixed prostheses in both maxillary and mandibular regions. MATERIALS AND METHODS: Thirty-five out of 38 patients who needed implant treatment and met inclusion criteria agreed to participate in the study and were consecutively enrolled. Surgical implant placement requirements consisted of a final torque of a least 25 Ncm prior to final seating and an implant stability quotient above 55. A total of 102 NanoTite PREVAIL (NTP) implants (BIOMET 3i, Palm Beach Gardens, FL, USA) (66 maxillary and 36 mandibular) were placed by one investigator, and the majority of these were placed in posterior regions (65%) and in soft bone (69%). A total of 44 prosthetic constructions were evaluated consisting of 14 single-tooth restorations, 26 fixed partial dentures, and four complete fixed restorations. All provisional constructions were delivered within 1 hour, and the final constructions placed after 4 months. Implants were monitored for clinical and radiographic outcomes at follow-up examinations scheduled for 3, 6, and 12 months. RESULTS: Of the 102 study implants, one implant failed. The simple cumulative survival rate value at 1 year was 99.2%. The average marginal bone resorption was 0.37 mm (SD 0.39) during the first year in function. According to the success criteria of Albrektsson and Zarb, success grade 1 was found with 93% of the implants. CONCLUSION: Although limited to the short follow-up, immediate loading of NanoTite Prevail implants seems to be a viable option in implant rehabilitation, at least when a good initial fixation is achieved.

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