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Bone density 11 years after anorexia nervosa onset in a controlled study of 39 cases.

Journal article
Authors Elisabet Wentz
Dan Mellström
Christopher Gillberg
Valter Sundh
I Carina Gillberg
Maria Råstam
Published in International Journal of Eating Disorders
Volume 34
Issue 3
Pages 314-318
ISSN 0276-3478
Publication year 2003
Published at Institute for the Health of Women and Children, Dept of Child and Adolescent Psychiatry
Institute of Community Medicine, Dept of Geriatric Medicine
Pages 314-318
Language en
Keywords Adolescent, Adult, Anorexia Nervosa, Complications, Body Composition, Body Weight, Bone Density, Bone Diseases, Metabolic, Etiology, Case-Control Studies, Female, Follow-Up Studies, Humans, Male, Risk Factors
Subject categories Psychiatry, Medical and Health Sciences


Objective To evaluate bone mineral density (BMD) and body composition 11 years after the onset of anorexia nervosa (AN). Method Thirty-nine AN subjects (36 females, 3 males), selected from a population-based sample, and 46 matched controls (COMP; 43 females, 3 males) were examined by using double-energy X-ray absorptiometry (DXA). Only 2 women still had AN. None of the men had AN. Results The females in the AN and COMP groups did not differ regarding BMD, nor was there a difference across female groups concerning body mass index (BMI). The female AN group had a significantly lower percentage of body fat. BMD among females in the AN group was related to lowest BMI ever. There was an inverse relationship between lumbar BMD and AN duration. Discussion Low BMD is not overrepresented among weight-restored AN patients at long-term follow-up compared with healthy women. However, the inverse relationship between BMD and AN duration may be indicative of a risk for osteopenia in patients with subchronic and chronic AN.

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