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Exosomes Communicate Protective Messages during Oxidative Stress; Possible Role of Exosomal Shuttle RNA.

Journal article
Authors Maria Eldh
Karin Ekström
Hadi Valadi
Margareta Sjöstrand
Bob Olsson
Margareta Jernås
Jan Lötvall
Published in PloS one
Volume 5
Issue 12
Pages e15353
ISSN 1932-6203
Publication year 2010
Published at Krefting Research Centre
Institute of Medicine, Department of Rheumatology and Inflammation Research
Institute of Clinical Sciences, Department of Biomaterials
Institute of Medicine, Department of Internal Medicine
Pages e15353
Language en
Subject categories Medical cell biology


Exosomes are small extracellular nanovesicles of endocytic origin that mediate different signals between cells, by surface interactions and by shuttling functional RNA from one cell to another. Exosomes are released by many cells including mast cells, dendritic cells, macrophages, epithelial cells and tumour cells. Exosomes differ compared to their donor cells, not only in size, but also in their RNA, protein and lipid composition.

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