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High risk of MS in Iranian immigrants in Gothenburg, Sweden.

Journal article
Authors Cecilia Ahlgren
Jan Lycke
Anders Odén
Oluf Andersen
Published in Multiple sclerosis journal
Volume 16
Issue 9
Pages 1079-1082
ISSN 1477-0970
Publication year 2010
Published at Institute of Neuroscience and Physiology, Department of Clinical Neuroscience and Rehabilitation
Department of Mathematical Sciences, Mathematical Statistics
Pages 1079-1082
Language en
Links dx.doi.org/10.1177/1352458510376777
Keywords Epidemiology, Iran, migration, multiple sclerosis, prevalence, Sweden
Subject categories Medical and Health Sciences

Abstract

BACKGROUND: In this study we investigated the risk of multiple sclerosis (MS) in migrants who had moved from Iran to Gothenburg, Sweden. METHODS: Patients born in Iran were retrieved from a population-based cohort, which included 534 MS and clinically isolated syndrome patients, born 1959-1990, aged 10-39 years at disease onset in Gothenburg. The expected versus observed number of migrants from Iran was calculated. RESULTS: The MS risk in the Iranian migrants in Gothenburg was several times higher than in Isfahan, Iran (hazard ratio 3.88, 95% confidence interval 2.17-6.40). Compared with the general population of Gothenburg, the observed number of 17 Iranian patients was higher than the expected value of 9.89 (hazard ratio 1.72, 95% confidence interval 1.00-2.75). CONCLUSION: Migration from a medium-risk to a high-risk area may increase the MS risk to that of the high-risk area.

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