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Association between the catechol-O-methyltransferase Val158Met polymorphism and panic disorder: A replication.

Journal article
Authors Kristina Annerbrink
Lars Westberg
Marie Olsson
Christer Allgulander
Sven Andersch
Ingemar Sjödin
Göran Holm
Elias Eriksson
Published in Psychiatry research
Volume 178
Issue 1
Pages 196-198
ISSN 0165-1781
Publication year 2010
Published at Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry
Institute of Neuroscience and Physiology, Department of Pharmacology
Pages 196-198
Language en
Links dx.doi.org/10.1016/j.psychres.2009....
Keywords Psychiatric genetics; Association study; Catecholamines; Anxiety
Subject categories Pharmacology and Toxicology

Abstract

The association between the catechol-O-methyltransferase Val158Met polymorphism and panic disorder was studied in a Swedish sample of 211 patients and 452 controls. We found a significant excess of the Val allele in both male and female patients, the latter but not the former finding being in line with previous studies.

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