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Development of an electrowetting-based microfluidic platform for magnetic immunoassays

Conference paper
Authors Vincent Schaller
Anke Sanz-Velasco
Alexei Kalaboukhov
Justin F. Schneiderman
Fredrik Öisjöen
Aldo Jesorka
Andrea Prieto Astalan
Peter Enoksson
Dag Winkler
Published in 13th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2009; Jeju; South Korea; 1 November 2009 through 5 November 2009
Pages 85-87
ISBN 978-097980642-1
Publication year 2009
Published at
Pages 85-87
Language en
Subject categories Magnetism, Fluid mechanics, Functional materials

Abstract

We report the transport of magnetic nanoparticles (MNPs) in suspension in a 2 μl de-ionized water droplet (DIWD) using ElectroWetting-On-Dielectic (EWOD) actuation, and the detection of the MNPs by magnetic AC-susceptibility measurements using a highly sensitive high-Tc dc Superconducting Quantum Interference Device (SQUID) gradiometer. These results constitute the first development step towards a MNP-based magnetic immunoassay platform with SQUID-readout and sample droplet handling.

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