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Classification of osseointegrated implant surfaces: materials, chemistry and topography

Review article
Authors David Dohan Ehrenfest
Paulo Coelho
Byung-Soo Kang
Young-Taeg Sul
Tomas Albrektsson
Published in Trends in Biotechnology
Volume 28
Issue 4
Pages 198-206
ISSN 0167-7799
Publication year 2010
Published at Institute of Clinical Sciences, Department of Biomaterials
Pages 198-206
Language en
Subject categories Biomaterials


Since the founding of the osseointegration concept, the characteristics of the interface between bone and implant, and possible ways to improve it, have been of particular interest in dental and orthopaedic implant research. Making use of standardized tools of analysis and terminology, we present here a standardized characterization code for osseointegrated implant surfaces. This code describes the chemical composition of the surface, that is, the core material, such as titanium, and its chemical or biochemical modification through impregnation or coating. This code also defines the physical surface features, at the micro- and nanoscale, such as microroughness, microporosity, nanoroughness, nanotubes, nanoparticles, nanopatterning and fractal architecture. This standardized classification system will allow to clarify unambiguously the identity of any given osseointegrated surface and help to identify the biological outcomes of each surface characteristic. Copyright © 2009 Elsevier Ltd. All rights reserved.

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