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Calcium aluminate coated and un-coated free form fabricated CoCr implants, a comparative study in rabbit

Journal article
Authors Anders Palmquist
T. Jarmar
L. Hermansson
Lena Emanuelsson
A. Taylor
M. Taylor
H. Engqvist
Peter Thomsen
Published in Journal of Biomedical Materials Research Part B: Applied Biomaterials
Volume 91
Issue 1
Pages 122-7
ISSN 1552-4981
Publication year 2009
Published at Institute of Clinical Sciences, Department of Biomaterials
Pages 122-7
Language en
Keywords CoCr; calcium aluminate; free form fabrication; FIB; TEM; bone
Subject categories Biomaterials Science, Clinical Medicine


The purpose of this study was to compare the integration in bone of uncoated free form fabricated cobalt chromium (CoCr) implants to the same implant with a calcium aluminate coating. The implants of cylindrical design with a pyramidal surface structure were press-fit into the limbs of New Zealand white rabbits. After 6 weeks, the rabbits were sacrificed, and samples were retrieved and embedded. Ground sections were subjected to histological analysis and histomorphometry. The section counter part was used for preparing an electron transparent transmission electron microscopy sample by focused ion beam milling. Calcium aluminate dip coating provided a significantly greater degree of bone contact than that of the native CoCr. The gibbsite hydrate formed in the hardening reaction of the calcium aluminate was found to be the exclusive crystalline phase material in direct contact with bone.

Page Manager: Webmaster|Last update: 9/11/2012

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