To the top

Page Manager: Webmaster
Last update: 9/11/2012 3:13 PM

Tell a friend about this page
Print version

Slowed reaction time in H… - University of Gothenburg, Sweden Till startsida
To content Read more about how we use cookies on

Slowed reaction time in HIV-1-infected patients without AIDS

Journal article
Authors Åsa Mellgren
Gunnar Norkrans
Lars Hagberg
O. Dunlop
Rune Wejstål
Magnus Gisslén
Published in Acta Neurol Scand
Volume 102
Issue 3
Pages 169-74
Publication year 2000
Published at Institute of Internal Medicine, Dept of Infectious Diseases
Pages 169-74
Language en
Keywords AIDS Dementia Complex/etiology, Adult, Aged, CD4 Lymphocyte Count, Case-Control Studies, Female, HIV Infections/complications/*psychology/virology, HIV-1/*isolation & purification, Hepatitis C, Chronic/psychology, Humans, Male, Middle Aged, *Psychomotor Performance, *Reaction Time, Statistics, Nonparametric
Subject categories Microbiology in the medical area


OBJECTIVES: To investigate if HIV-1-infected patients without acquired immunodeficiency syndrome (AIDS) have cerebral dysfunction as reflected by impaired reaction times compared to patients with chronic hepatitis C. MATERIAL AND METHODS: Forty-one HIV-1-infected patients not fulfilling the AIDS criteria, were tested with three reaction time tests and compared to controls with chronic hepatitis C, matched according to gender and age. RESULTS: HIV-1-infected individuals had, in mean, 5-47 ms longer reaction time than patients with hepatitis C (statistically significant in two of three tests). All but 9 HIV-1-infected individuals had, however, reaction times within the normal range defined by the control group (mean +/- 2 SD). No correlation was found between reaction time and immune status measured as CD4-cell count. CONCLUSION: This study indicates that a subgroup of HIV-1-infected individuals have slower reaction time compatible with cerebral deterioration early in the course of the infection.

Page Manager: Webmaster|Last update: 9/11/2012

The University of Gothenburg uses cookies to provide you with the best possible user experience. By continuing on this website, you approve of our use of cookies.  What are cookies?