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Three-year folow-up of posterior capsule opacification with two different silicone intraocular lenses.

Journal article
Authors Karin Sundelin
H Shams
Ulf Stenevi
Published in Acta Ophthalmologica Scandinavica
Volume 83
Pages 11-19
ISSN pISSN: 1395-3907
Publication year 2005
Published at Institute of Clinical Neurosciences, Section of Ophtalmology
Pages 11-19
Language en
Links doi: 10.1111/j.1600-0420.2005.00408...
Keywords posterior capsule opacification (PCO) – silicone – intraocular lens (IOL) – longterm
Subject categories Medical and Health Sciences


ABSTRACT. Purpose: To compare posterior capsule opacification (PCO) after cataract surgery with implantation of two silicone intraocular lenses (IOLs) with different designs. Methods: We carried out a prospective, clinical study of 116 patients randomized to standardized phacoemulsification with implantation of CeeOn Edge (n = 57) or SI40NB (n = 59) IOLs. The follow-up period was 3 years. To evaluate PCO morphologically, digital images were obtained and analysed using evaluation of posterior capsule opacification computer software (EPCO). The neodymium: YAG (Nd:YAG) capsulotomy rate was recorded. Results: At 2 and 3 years, the eyes with SI40NB IOLs had significantly more PCO than those with the CeeOn Edge IOLs (p = 0.00014 and p = 0.002). Nine Nd:YAG capsulotomies were performed in the SI40NB group and none in the CeeOn Edge group. This difference was statistically significant (p = 0.003). In some patients a regression of PCO was noticed and confirmed using EPCO. Statistically less PCO was noted when the capsulorhexis rim was placed so that it covered all 360 degrees of the optic of the IOL. Conclusions: A clinically and statistically significant difference in PCO development between CeeOn Edge and SI40NB IOLs at 2 and 3 years postoperatively was found. These findings support earlier studies indicating that a sharp edge of the optic is a more important factor in IOL design than IOL material in the prevention of PCO. Key words: posterior capsule opacification (PCO) – silicone – intraocular lens (IOL) – longterm follow-up – prospective – evaluation of posterior capsule opacification (EPCO) – capsulotomy – optic edge – regression

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