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Well-differentiated Neuroendocrine Carcinoma of the Larynx: Confusion of Terminology and Uncertainty of Early Studies

Journal article
Authors J. L. Hunt
L. Barnes
A. Triantafyllou
D. R. Gnepp
K. O. Devaney
Göran Stenman
G. B. Halmos
J. A. Bishop
A. Skalova
S. M. Willems
H. Hellquist
A. Rinaldo
A. Ferlito
Published in Advances in Anatomic Pathology
Volume 26
Issue 4
Pages 246-250
ISSN 1072-4109
Publication year 2019
Published at Institute of Biomedicine, Department of Pathology
Pages 246-250
Language en
Links dx.doi.org/10.1097/pap.000000000000...
Keywords carcinoid, atypical carcinoid, small cell neuroendocrine carcinoma, large cell neuroendocrine, neoplasms, tumor, diagnosis, cells, neck, head, Pathology
Subject categories Cancer and Oncology

Abstract

Well-differentiated neuroendocrine carcinoma (also known as "carcinoid") of the larynx is an exceedingly rare tumor that has an epithelial origin. These tumors are malignant and have a low, but definite, risk of metastasis. Although it can be challenging, this tumor should be differentiated from moderately differentiated neuroendocrine carcinoma (also known as "atypical carcinoid"). The clinical and pathologic features of this tumor, as well as treatment and prognosis, are reviewed in detail.

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