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Bowel Obstruction and Ventral Hernia After Laparoscopic Versus Open Surgery for Rectal Cancer in A Randomized Trial (COLOR II).

Journal article
Authors Josefin Petersson
Thomas W Koedam
H Jaap Bonjer
John Andersson
Eva Angenete
David Bock
Miguel A Cuesta
Charlotte L Deijen
Alois Fürst
Antonio M Lacy
Jacob Rosenberg
Eva Haglind
Published in Annals of surgery
Volume 269
Issue 1
Pages 53–57
ISSN 1528-1140
Publication year 2019
Published at Institute of Clinical Sciences, Department of Surgery
Pages 53–57
Language en
Subject categories Surgery


The aim of this study was to evaluate the risk of bowel obstruction, incisional, and parastomal hernia following laparoscopic versus open surgery for rectal cancer.Laparoscopic surgery for rectal cancer has been adopted worldwide, after trials reported similar oncological outcomes compared with open surgery. Little is known about long-term morbidity, including bowel obstruction, incisional, and parastomal hernia following surgery.Patients included in the international, multicenter, noninferior, open-label, randomized COLOR II trial were followed for five years. Primary endpoint was local recurrence at 3-year follow-up. Secondary endpoints included bowel obstruction, incisional and parastomal hernia within 5 years, and the current article reports on these secondary endpoints.All 1044 patients included in the COLOR II trial were analyzed. There was no difference in risk of bowel obstruction, incisional, or parastomal hernia following laparoscopic or open surgery for rectal cancer.Based on long-term morbidity outcomes, laparoscopic surgery for rectal cancer could be considered a routine technique as there are no differences with open surgery.

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