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Green listed-a CRISPR screen tool

Journal article
Authors S. K. Panda
S. V. Boddul
G. Y. Jimenez-Andrade
L. Jiang
Z. Kasza
Luciano Francisco Fernandez Ricaud
F. Wermeling
Published in Bioinformatics
Volume 33
Issue 7
Pages 1099-1100
ISSN 1367-4803
Publication year 2017
Published at Department of marine sciences
Pages 1099-1100
Language en
Links 10.1093/bioinformatics/btw739
Keywords human genome, activation, immunity
Subject categories Biochemistry and Molecular Biology, Chemical Sciences

Abstract

Motivation: Genome editing using versions of the bacterial CRISPR/Cas9 system can be used to probe the function of selected genes in any organism.Green Listed is a web-based tool that rapidly designs custom CRISPR screens targeting sets of genes defined by the user. It could thus be used to design screens targeting for example all genes differentially expressed during a specific stimuli or all genes related to a specific pathway or function, as well as to generate targeted secondary screens following a large-scale screen.

Page Manager: Webmaster|Last update: 9/11/2012
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