To the top

Page Manager: Webmaster
Last update: 9/11/2012 3:13 PM

Tell a friend about this page
Print version

Flavonoids from Erythrina… - University of Gothenburg, Sweden Till startsida
Sitemap
To content Read more about how we use cookies on gu.se

Flavonoids from Erythrina schliebenii

Journal article
Authors Stephen S. Nyandoro
Joan J. E. Munissi
M. Kombo
C. A. Mgina
F. F. Pan
Amra Gruhonjic
Paul A. Fitzpatrick
Y. Lu
B. Wang
K. Rissanen
Mate Erdelyi
Published in Journal of Natural Products
Volume 80
Issue 2
Pages 377-383
ISSN 0163-3864
Publication year 2017
Published at Swedish NMR Centre at Göteborg University
Sahlgrenska Cancer Center
Department of Chemistry and Molecular Biology
Pages 377-383
Language en
Keywords stem bark, caffra thunb, pterocarpan, isoflavanones, isoflavones, orientalis, addisoniae, sacleuxii, tanzania, Plant Sciences, Pharmacology & Pharmacy
Subject categories Biochemistry and Molecular Biology

Abstract

Prenylated and O-methylflavonoids including one new pterocarpan (1), three new isoflavones (2-4), and nineteen known natural products (5-23) were isolated and identified from the root, stem bark, and leaf extracts of Erythrina schliebenii. The crude extracts and their constituents were evaluated for antitubercular activity against Mycobacterium tuberculosis (H37Rv strain), showing MICs of 32-64 mu g mL(-1) and 36.9-101.8 mu M, respectively. Evaluation of their toxicity against the aggressive human breast cancer cell line MDA-MB-231 indicated EC50 values of 13.0-290.6 mu M (pure compounds) and 38.3 to >100 mu g mL(-1) (crude extracts). RAMSON D, 1973, PHYTOCHEMISTRY, V12, P2211

Page Manager: Webmaster|Last update: 9/11/2012
Share:

The University of Gothenburg uses cookies to provide you with the best possible user experience. By continuing on this website, you approve of our use of cookies.  What are cookies?