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Bestrophin-3 is differently expressed in normal and injured mouse glomerular podocytes.

Journal article
Authors Veronika Golubinskaya
Johannes Elvin
Kerstin Ebefors
Helena Gustafsson
Carina Mallard
Jenny Nyström
Holger Nilsson
Published in Acta physiologica (Oxford, England)
Volume 214
Issue 4
Pages 481–496
ISSN 1748-1716
Publication year 2015
Published at Institute of Neuroscience and Physiology, Department of Physiology
Institute of Medicine, Department of Molecular and Clinical Medicine
Pages 481–496
Language en
Keywords LPS, alternative splicing, ER stress, nestin, bestrophin-3, podocyte
Subject categories Physiology


Bestrophins are putative calcium-activated chloride channels. Recently cell-protective functions for Bestrophin-3 (Best3) were proposed. Best3 exists in different splice variants. We have here examined expression, alternative splicing and localization of Best3 in mouse podocytes under normal conditions and during endoplasmic reticulum (ER) stress.

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