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Histone Deacetylase Inhibitor Treatment Increases Coronary t-PA Release in a Porcine Ischemia Model.

Journal article
Authors Kristina Svennerholm
Niklas Bergh
Pia Larsson
Sverker Jern
Göran Johansson
Björn Biber
Michael Haney
Published in PloS one
Volume 9
Issue 5
Pages e97260
ISSN 1932-6203
Publication year 2014
Published at Institute of Clinical Sciences, Department of Anesthesiology and Intensive care
Institute of Medicine, Department of Molecular and Clinical Medicine
Pages e97260
Language en
Subject categories Cardiovascular medicine


The expression of the tissue plasminogen activator gene can be affected by histone deacetylation inhibition and thus appears to be under epigenetic control.

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