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Is Marginal Bone Loss around Oral Implants the Result of a Provoked Foreign Body Reaction?

Journal article
Authors Tomas Albrektsson
Christer Dahlin
Torsten Jemt
Lars Sennerby
Alberto Turri
Ann Wennerberg
Published in Clinical implant dentistry and related research
Volume 16
Issue 2
Pages 155–165
ISSN 1708-8208
Publication year 2014
Published at Institute of Odontology
Institute of Clinical Sciences, Department of Biomaterials
Pages 155–165
Language en
Keywords bone loss;dental implants;foreign body reaction;osseointegration;peri-implantitis
Subject categories Biomaterials


When a foreign body is placed in bone or soft tissue, an inflammatory reaction inevitably develops. Hence, osseointegration is but a foreign body response to the implant, which according to classic pathology is a chronic inflammatory response and characterized by bone embedding/separation of the implant from the body.

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