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Contrast echocardiography reveals apparently normal coronary perfusion in a rat model of stress-induced (Takotsubo) cardiomyopathy.

Journal article
Authors Björn Redfors
Yangzhen Shao
Johannes Wikström
Alexander R Lyon
Anders Oldfors
Li-Ming Gan
Elmir Omerovic
Published in European heart journal cardiovascular Imaging
Volume 15
Issue 2
Pages 152-157
ISSN 2047-2412
Publication year 2014
Published at Institute of Biomedicine
Institute of Medicine, Department of Molecular and Clinical Medicine
Pages 152-157
Language en
Links dx.doi.org/10.1093/ehjci/jet079
Keywords Animal models of cardiovascular disease, Catecholamines, Echocardiography, Tako-tsubo syndrome
Subject categories Cardiovascular medicine

Abstract

Stress-induced cardiomyopathy (SIC) is an important differential diagnosis to acute myocardial infarction (AMI) that is associated with significant morbidity and mortality. The typical hallmark of SIC is left-ventricular apical akinesia but preserved function in basal segments. Catecholamines are postulated to play an important role in SIC but the precise pathophysiology is incompletely understood. Whether myocardial perfusion of the affected segments is impaired in SIC has been debated and remains unknown.

Page Manager: Webmaster|Last update: 9/11/2012
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