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A clinical case series of six extremely aggressive youths treated with olanzapine

Journal article
Authors Henrik Söderström
Maria Råstam
Christopher Gillberg
Published in European Child and Adolescent Psychiatry
Volume 11
Issue 3
Pages 138-141
ISSN 1018-8827
Publication year 2002
Published at Institute for the Health of Women and Children, Dept of Child and Adolescent Psychiatry
Pages 138-141
Language en
Keywords Olanzapine, Violence, Aggression, Neuropsychiatry, Adolescents
Subject categories Medical and Health Sciences, Psychiatry, Child and adolescent psychiatry

Abstract

Olanzapine is an atypical neuroleptic drug with mood-stabilising properties and few of the side effects commonly associated with conventional neuroleptic treatment. We used olanzapine, 5-20 mg/day, to treat severe aggression in six non-psychotic teenage boys with neuropsychiatric disorders. All but one started to respond within one week. The therapeutic effect in four of the patients clearly outweighed the side effects (weight gain and sedation). The subjects described a markedly increased sense of well being during the olanzapine treatment.

Page Manager: Webmaster|Last update: 9/11/2012
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