To the top

Page Manager: Webmaster
Last update: 9/11/2012 3:13 PM

Tell a friend about this page
Print version

Meta-analysis of neurobla… - University of Gothenburg, Sweden Till startsida
Sitemap
To content Read more about how we use cookies on gu.se

Meta-analysis of neuroblastomas reveals a skewed ALK mutation spectrum in tumors with MYCN amplification.

Journal article
Authors Sara De Brouwer
Katleen De Preter
Candy Kumps
Piotr Zabrocki
Michaël Porcu
Ellen M Westerhout
Arjan Lakeman
Jo Vandesompele
Jasmien Hoebeeck
Tom Van Maerken
Anne De Paepe
Geneviève Laureys
Johannes H Schulte
Alexander Schramm
Caroline Van Den Broecke
Joëlle Vermeulen
Nadine Van Roy
Klaus Beiske
Marleen Renard
Rosa Noguera
Olivier Delattre
Isabelle Janoueix-Lerosey
Per Kogner
Tommy Martinsson
Akira Nakagawara
Miki Ohira
Huib Caron
Angelika Eggert
Jan Cools
Rogier Versteeg
Frank Speleman
Published in Clinical cancer research : an official journal of the American Association for Cancer Research
Volume 16
Issue 17
Pages 4353-62
ISSN 1078-0432
Publication year 2010
Published at Institute of Biomedicine, Department of Medical and Clinical Genetics
Pages 4353-62
Language en
Links dx.doi.org/10.1158/1078-0432.CCR-09...
Keywords neuroblastom, alk
Subject categories Medical Genetics, Molecular medicine

Abstract

Activating mutations of the anaplastic lymphoma kinase (ALK) were recently described in neuroblastoma. We carried out a meta-analysis of 709 neuroblastoma tumors to determine their frequency and mutation spectrum in relation to genomic and clinical parameters, and studied the prognostic significance of ALK copy number and expression.

Page Manager: Webmaster|Last update: 9/11/2012
Share:

The University of Gothenburg uses cookies to provide you with the best possible user experience. By continuing on this website, you approve of our use of cookies.  What are cookies?