To the top

Page Manager: Webmaster
Last update: 9/11/2012 3:13 PM

Tell a friend about this page
Print version

3-methylcrotonyl-CoA carb… - University of Gothenburg, Sweden Till startsida
Sitemap
To content Read more about how we use cookies on gu.se

3-methylcrotonyl-CoA carboxylase deficiency and severe multiple sclerosis.

Journal article
Authors Niklas Darin
Oluf Andersen
Lars-Martin Wiklund
Daniel Holmgren
Elisabeth Holme
Published in Pediatric neurology
Volume 36
Issue 2
Pages 132-4
ISSN 0887-8994
Publication year 2007
Published at Institute of Neuroscience and Physiology, Department of Clinical Neuroscience and Rehabilitation
Institute of Clinical Sciences, Department of Pediatrics
Institute of Clinical Sciences
Pages 132-4
Language en
Links dx.doi.org/10.1016/j.pediatrneurol....
Keywords Adjuvants, Immunologic, therapeutic use, Adolescent, Analgesics, therapeutic use, Brain, pathology, Carbon-Carbon Ligases, deficiency, Female, Humans, Interferon-beta, therapeutic use, Magnetic Resonance Imaging, Metabolism, Inborn Errors, complications, pathology, Mitoxantrone, therapeutic use, Multiple Sclerosis, Relapsing-Remitting, complications, drug therapy, pathology, Steroids, therapeutic use
Subject categories Medical and Health Sciences

Abstract

This report describes a female with isolated 3-methylcrotonyl-CoA carboxylase deficiency. She had a mild Reye-like episode, loss of scalp hair, psychomotor retardation, and an attention-deficit hyperactivity disorder. The diagnosis was made at 13 years of age when she developed relapsing remitting multiple sclerosis with a malignant course. Treatment with steroids had initially a good therapeutic effect on the relapses. The response to interferon beta-1a treatment was poor. On mitoxantrone treatment there was a considerable neurologic recovery.

Page Manager: Webmaster|Last update: 9/11/2012
Share:

The University of Gothenburg uses cookies to provide you with the best possible user experience. By continuing on this website, you approve of our use of cookies.  What are cookies?

Denna text är utskriven från följande webbsida:
http://www.gu.se/english/research/publication/?publicationId=51183
Utskriftsdatum: 2020-08-12