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Brown Adipose Reporting Criteria in Imaging STudies (BARCIST 1.0): Recommendations for Standardized FDG-PET/CT Experiments in Humans

Journal article
Authors K. Y. Chen
A. M. Cypess
M. R. Laughlin
C. R. Haft
H. H. Hu
M. A. Bredella
Sven Enerbäck
P. E. Kinahan
W. V. Lichtenbelt
F. I. Lin
J. J. Sunderland
K. A. Virtanen
R. L. Wahl
Published in Cell Metabolism
Volume 24
Issue 2
Pages 210-222
ISSN 1550-4131
Publication year 2016
Published at Institute of Biomedicine
Pages 210-222
Language en
Links dx.doi.org/10.1016/j.cmet.2016.07.0...
Keywords positron-emission-tomography, type-2 diabetes-mellitus, adult humans, f-18-fdg pet/ct, energy-expenditure, oxidative-metabolism, insulin, sensitivity, computed-tomography, tissue activity, cold-exposure, Cell Biology, Endocrinology & Metabolism
Subject categories Clinical Medicine, Biological Sciences

Abstract

Human brown adipose tissue (BAT) presence, metabolic activity, and estimated mass are typically measured by imaging [18F]fluorodeoxyglucose (FDG) uptake in response to cold exposure in regions of the body expected to contain BAT, using positron emission tomography combined with X-ray computed tomography (FDG-PET/CT). Efforts to describe the epidemiology and biology of human BAT are hampered by diverse experimental practices, making it difficult to directly compare results among laboratories. An expert panel was assembled by the National Institute of Diabetes and Digestive and Kidney Diseases on November 4, 2014 to discuss minimal requirements for conducting FDG-PET/CT experiments of human BAT, data analysis, and publication of results. This resulted in Brown Adipose Reporting Criteria in Imaging STudies (BARCIST 1.0). Since there are no fully validated best practices at this time, panel recommendations are meant to enhance comparability across experiments, but not to constrain experimental design or the questions that can be asked.

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Denna text är utskriven från följande webbsida:
http://www.gu.se/english/research/publication/?publicationId=242322
Utskriftsdatum: 2019-10-17