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Multivariate outbreak detection

Report
Authors Linus Schiöler
Marianne Frisén
Publisher University of Gothenburg
Place of publication Göteborg
Publication year 2010
Published at Department of Economics, Statistical Research Unit
Language en
Links hdl.handle.net/2077/23390
Subject categories Statistics

Abstract

On-line monitoring is needed to detect outbreaks of diseases like influenza. Surveillance is also needed for other kinds of outbreaks, in the sense of an increasing expected value after a constant period. Information on spatial location or other variables might be available and may be utilized. We adapted a robust method for outbreak detection to a multivariate case. The relation between the times of the onsets of the outbreaks at different locations (or some other variable) was used to determine the sufficient statistic for surveillance. The derived maximum likelihood estimator of the outbreak regression was semi-parametric in the sense that the baseline and the slope were non-parametric while the distribution belonged to the exponential family. The estimator was used in a generalized likelihood ratio surveillance method. The method was evaluated with respect to robustness and efficiency in a simulation study and applied to spatial data for detection of influenza outbreaks in Sweden.

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Denna text är utskriven från följande webbsida:
http://www.gu.se/english/research/publication/?publicationId=131556
Utskriftsdatum: 2019-10-20